yes that is possible.
But when you look at the setup, you have 2 separate connections:
1. Openflier to OS which is a SAN-type connection
2. OS to Clients which is NAS-type connection
So yes, of course it is possible.
But in a SAN or sometimes referred to as "storage network" you need different NIC settings - larger MTU (9000 is what is most compatible these days), TOE Options to a certain extent, Link Aggregation etc.
In an NAS environment because you usually have a large mix of clients, it is best not to fiddle with the MTU size, and disable TOE altogether, because from my professional experience it is the number 1 cause of surprisingly low network performance.
Therefore we still draw a fat red line between the both.
Just my 2 cents.