No, I didnt not recommend using 6-8 drives in a RAID 0 array. From what you said "For absolute performance, I would suggest that you consider RAID 1+0 over just RAID 0" I think that is not to be true. If you took 6 drives and make an array in RAID 0, it would be faster then 6 drives of a RAID 1+0 array. You claim that to be false, correct? After a little bit, I will do testing of this theory and make sure I am correct in my statement.
About losing data, I would hope that I made it clear that RAID 0 is by no means the place to store critical data. From what I gathered, it sounds like he is willing to take a little bit more risk to reap the performance benefits. From my own person experience, if one is to keep a drive cool and properly installed, drive will last longer them if they are not. I currently have 20 drives in a RAID 0 set as well as a set of 15 drives in RAID 0. On those arrays, I have nothing of any importance or nothing that isnt backed on up elsewhere. All I can say is that I have had good luck with properly cooled and mounted drives.